BPC-157 is a gastric pentadecapeptide that has been found to have positive effects on growth hormones and healing properties in various medical conditions such as spinal cord injury and burn wounds.

In a study involving rats, BPC-157 was administered in doses of 0, 0.1, 0.25, and 0.5 micrograms/mL over 24 hours. Results showed that the 0.5 microgram/mL dose significantly increased growth hormone expression from day 1 to day 3, while lower doses also had similar effects. The study concluded that BPC-157 supplementation led to increased up-regulation of growth hormone in a dose and time-dependent manner.

Researchers are unsure of the exact process of how BPC-157 facilitates healing, but real-time PCR, Western Blot Analysis, and MTT assay showed increased healing and growth in tendon fibroblasts of rats treated with BPC-157.

In a separate study, BPC-157 was injected into spinal cord lesions of rats, resulting in increased motor function and rescue in the tail compared to rats injected with saline. Similar effects were observed with neural stem cell or bone marrow stromal cell injections.

The study also found that BPC-157 had beneficial effects on muscle function, counteracting the negative effects of inflammatory cytokines associated with various types of trauma. This suggests that BPC-157 could facilitate healing in various other muscular injuries that would not normally heal on their own.